Search results for: 'ATM'
- CGK733Catalog No. :A8624ATM/ATR inhibitor,potent and selective
CGK733 is an inhibitor of kinase ATM and ATR with IC50 value of ~200 nM .
- AZD8055Catalog No. :A8214MTOR inhibitor
AZD8055 is a selective inhibitor of mTOR kinase with IC50 of 0.8 nM . It competes with ATP at the ATP-binding cleft of mTOR. AZD8055 showed ~1000 fold selectivity against closely related kinases PI3K isoforms and ATM/DNA-PK . Furthermore, it had no significant activity against a panel of 260 kinases at 10 μM .