- Hippo Signaling(1)
- Cancer stem cell(3)
- Cat.No. Product Name Information
- B1249 TDZD-8 TDZD-8 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) with IC50 value of 1.4μM .
- B1540 TWS119 TWS119 is an inhibitor of glycogen synthase kinase-3β (GSK-3β) with IC50 value of 30nM .
- B2305 IWP-L6 IWP-L6 is an inhibitor of Porcupine with IC50 value of 0.5nM .
- B3083 FLI-06 FLI-06 is a novel inhibitor of Notch signaling with EC50 value of 2.3uM .
Wnt-C59 is a selective inhibitor of Wnt signaling with IC50 value of 74 pM .
- A8659 SANT-1 Potent, cell-permeable inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (KD = 1.2 nM).
- A8658 AY 9944 dihydrochloride Inhibitor of hedgehog (Hh) signaling, possibly via several mechanisms.
- A8657 AZ 12080282 dihydrochloride Inhibitor of Hedgehog (Hh) signaling (IC50 <0.012 μM in a firefly reporter assay against the Hh pathway).
- A8656 Jervine Inhibitor of Hedgehog signaling (IC50 = 500 - 700 nM); binds directly to Smoothened (Smo).
- A8655 Ciliobrevin A Hedgehog (Hh) pathway antagonist; blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of Smo.