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Proteases

Proteases, also known as peptidases or proteolytic enzymes, consists of a large number of enzymes catalyzing the hydrolysis of peptide bonds and subsequently resulting in the degradation of protein substrates into amino acids. Proteases are involved in a wide range of human diseases, including cancer, neurodegenerative disorders, inflammatory diseases and cardiovascular diseases. Thus numerous proteases inhibitors (small molecules and proteins) have been identified to block activity of proteases. Proteases inhibitors can be classified into different types based on the class of proteases they inhibit through two general mechanisms, irreversible “trapping” reactions and reversible tight-binding reactions. Proteases inhibitors have been used as diagnostic or therapeutic agents for the treatment of proteases-related diseases.

Products for  Proteases

product-structure
  1. Cat.No. Product Name Information
  2. A1930 Apoptosis Inhibitor Associate with caspase-3 inhibition
  3. A2574 Aprotinin Inhibitor of bovine pancreatic trypsin
  4. A8363 Argatroban Thrombin mediated fibrinogen cleavage inhibitor
  5. A4432 ARP 100 Selective MMP-2 inhibitor
  6. A4433 ARP 101 MMP inhibitor,potent and selective
  7. C4189 Arphamenine B (hemisulfate) aminopeptidase B inhibitor
  8. A3195 Asunaprevir (BMS-650032) NS3 protease inhibitor
  9. A4056 AT13387 Hsp90 inhibitor
  10. A8205 Atazanavir HIV protease inhibitor,highly potent
  11. A4040 Atazanavir sulfate (BMS-232632-05) Protease inhibitor

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