Chromatin/Epigenetics
Epigenetics
Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.
Products for Chromatin/Epigenetics
- Bromodomain(41)
- Aurora Kinase(35)
- DNA Methyltransferase(14)
- HDAC(66)
- Histone Acetyltransferases(21)
- Histone Demethylases(33)
- Histone Methyltransferase(53)
- HIF(17)
- JAK(49)
- MBT Domains(1)
- PARP(35)
- Pim(13)
- Protein Ser/Thr Phosphatases(34)
- RNA Polymerase(7)
- Sirtuin(26)
- Sphingosine Kinase-2(1)
- Polycomb repressive complex(2)
- SUMOylation(2)
- PAD(1)
- Cat.No. Product Name Information
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A4508
ML 228
HIF pathway activator
-
A4507
KC7F2
HIF-1α inhibitor
-
A4505
Chetomin
A4505 inhibitor
-
A4501
Tubacin
HDAC6 inhibitor,potent,selective,reversible,cell-permeable
-
A3821
SRT2104 (GSK2245840)
SIRT1 activator,selective
-
A3760
Reversine
A3 adenosine receptor antagonist,ARK-1/-2/-3 inhibitor
-
A3556
LKB1 (AAK1 dual inhibitor)
Pim-1 kinase inhibitor
-
A3338
CX-6258 hydrochloride hydrate
Pan-Pim kinases Inhibitor
-
A3337
CX-6258
Pan-Pim kinases Inhibitor
-
A3214
AZD1152
Aurora B kinase inhibitor,highly potent and selective
