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Chromatin/Epigenetics

Epigenetics

Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.

Products for  Chromatin/Epigenetics

  1. Cat.No. Product Name Information
  2. A4508 ML 228 HIF pathway activator
  3. A4507 KC7F2 HIF-1α inhibitor
  4. A4505 Chetomin A4505 inhibitor
  5. A4501 Tubacin HDAC6 inhibitor,potent,selective,reversible,cell-permeable
  6. A3821 SRT2104 (GSK2245840) SIRT1 activator,selective
  7. A3760 Reversine A3 adenosine receptor antagonist,ARK-1/-2/-3 inhibitor
  8. A3556 LKB1 (AAK1 dual inhibitor) Pim-1 kinase inhibitor
  9. A3338 CX-6258 hydrochloride hydrate Pan-Pim kinases Inhibitor
  10. A3337 CX-6258 Pan-Pim kinases Inhibitor
  11. A3214 AZD1152 Aurora B kinase inhibitor,highly potent and selective

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