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Chromatin/Epigenetics

Epigenetics

Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.

Products for  Chromatin/Epigenetics

product-structure
  1. Cat.No. Product Name Information
  2. A1908 AMI-1 PRMT1 inhibitor
  3. B6085 AMI5/Eosin Y disodium salt protein methyltransferase inhibitor/dye,used in HE staining
  4. A4488 Anacardic acid HAT inhibitor
  5. A8176 Apicidin Potent HDAC inhibitor
  6. A4104 AR-42 (OSU-HDAC42) HDAC inhibitor,novel and potent
  7. B6084 AS8351 histone demethylase inhibitor
  8. A4117 AT9283 Aurora kinase/JAK inhibitor
  9. A4126 Aurora A Inhibitor I Aurora A inhibitor
  10. A4144 AZ 960 JAKs inhibitor
  11. B1255 AZ505 SMYD2 inhibitor,potent and selective

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