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Chromatin/Epigenetics

Epigenetics

Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.

Products for  Chromatin/Epigenetics

  1. Cat.No. Product Name Information
  2. A4537 Fumonisin B1 PP5/PP2Cα/PP2A/PP1γ2/PP2B inhibitor
  3. A4536 Fostriecin sodium salt Antitumor antibiotic
  4. A4535 DL-AP3 Glutamate receptor antagonist and HPSP inhibitor
  5. A4534 Ceramide Protein phosphatase and CAPP modulator
  6. A4533 Calyculin A Protein phosphatase inhibitor
  7. A4532 Calcineurin Autoinhibitory Peptide CaMKII inhibitor
  8. A4518 UNC 926 hydrochloride Inhibitor of methyl lysine reader domain
  9. A4517 ZM 449829 JAK3 inhibitor
  10. A4513 Lestaurtinib JAK2/FLT3/TrkA inhibitor
  11. A4509 PX 12 Trx-1 inhibitor

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