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Chromatin/Epigenetics

Epigenetics

Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.

Products for  Chromatin/Epigenetics

product-structure
  1. Cat.No. Product Name Information
  2. B1182 ABC294640 Sphingosine kinase 2 inhibitor,selective and competitive
  3. A3002 ABT-888 (Veliparib) Potent PARP inhibitor
  4. B5936 ACY-241 Selective and orally active HDAC6 inhibitor
  5. B6120 Adox indirect methyltransferase inhibitor
  6. A4158 AG-14361 Potent PARP1 inhibitor
  7. B7323 AGK 2 SIRT2 inhibitor, potent and selective
  8. C5709 AGK7 cell-permeable, selective inhibitor of SIRT2
  9. B4713 AK-7 selective and brain-permeable SIRT2 inhibitor
  10. A4542 Alexidine dihydrochloride PTPMT1 inhibitor
  11. A4119 AMG-900 Aurora kinase inhibitor

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