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Chromatin/Epigenetics

Epigenetics

Epigenetics means above genetics. It determines how much and whether a gene is expressed without changing DNA sequences. Epigenetic regulations include, 1. DNA methylation: the addition of methyl group to DNA, converting cytosine to 5-methylcytosine, mostly at CpG sites; 2. Histone modifications: posttranslational modificationEpigeneticss of histone proteins including acetylation, methylation, ubiquitylation, phosphorylation and sumoylation; 3. miRNAs: non-coding microRNA downregulating gene expression; 4. Prions: infectious proteins viewed as epigenetic agents capable of inducing a phenotype without changing the genome.

Products for  Chromatin/Epigenetics

  1. Cat.No. Product Name Information
  2. A8191 Nanaomycin A DNMT3B inhibitor
  3. A4547 Thiolutin RNA polymerase inhibitor,antibiotic
  4. A4546 Mithramycin A Anticancer antibiotic
  5. A4544 NSC 87877 Shp2 /shp1 PTP inhibitor
  6. A4543 BVT 948 PTPs inhibitor,cell-permeable and non-competitve
  7. A4542 Alexidine dihydrochloride PTPMT1 inhibitor
  8. A4541 Sal 003 Cellular phosphatase complex inhibitor
  9. A4540 Okadaic acid Protein phosphatase 1 inhibitor
  10. A4539 NFAT Inhibitor NFAT inhibitor
  11. A4538 INCA-6 Selective calcineurin-NFAT signaling inhibitor

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