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Neuroscience

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides). read more

Products for  Neuroscience

  1. Cat.No. Product Name Information
  2. A3316 Clemizole hydrochloride H1 histamine receptor antagonist
  3. B2236 Desvenlafaxine Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively.
  4. B2246 Desvenlafaxine Succinate Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.
  5. B2250 LY310762 LY310762 is a 5-HT1D receptor antagonist with Ki of 249 nM, having a weaker affinity for 5-HT1B receptor.
  6. B2253 Prucalopride 5-HT4A and 5-HT4B receptor agonist
  7. B2255 SB271046 5-HT6 receptor antagonist, orally active
  8. B2259 VUF 10166 VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Ki of 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower.
  9. B2260 WAY-100635 Maleate 5-HT1A receptor agonist
  10. B2233 Azasetron HCl 5-HT3 receptor antagonist
  11. B2243 Almotriptan Malate 5-HT1B/1D-receptor agonist
  12. B2241 Ondansetron Ondansetron(GR38032) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.
  13. B2230 Trazodone HCl Antidepressant
  14. B2234 Clomipramine HCl SERT/NET dopamine transporter (DAT) blocker
  15. B2263 BMY 7378 5-HT1A partial agonist and α1D adrenoceptor antagonist
  16. B2231 Amitriptyline HCl Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor
  17. B2261 Zolmitriptan Zolmitriptan, a selective serotonin receptor agonist, is used to treat migraine attacks with or without aura and cluster headaches.
  18. B2237 Eletriptan HBr Eletriptan hydrobromide is a orally active, selective 5-HT1B/1D receptor agonist.
  19. B2229 Palonosetron HCl Palonosetron Hcl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).
  20. B1754 Fenspiride HCl Fenspiride Hcl is an α adrenergic and H1 histamine receptor antagonist.
  21. B1204 Ondansetron hydrochloride dihydrate Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.
  22. B1002 Tropisetron Hydrochloride Tropisetron is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
  23. B1477 Lurasidone HCl Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor
  24. B2258 Tropisetron Tropisetron(SDZ-ICS 930) is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
  25. B1205 Fluvoxamine serotonin reuptake inhibitor and σ₁ receptor agonist
  26. B1206 Pizotifen Pizotifen(Pizotyline) is a highly selective 5-HT receptor blocking agent, which is a benzocycloheptane based drug.
  27. B2007 Pizotifen Malate Pizotifen malate is a highly selective 5-HT receptor blocking agent, which is a benzocycloheptane based drug.
  28. B1059 Mosapride Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
  29. B2251 Naratriptan Naratriptan hydrochloride is a selective 5-HT1 receptor subtype agonist and is a triptan drug that is used for the treatment of migraine headaches.
  30. B2242 Urapidil HCl Urapidil HCl is an α1-adrenoceptor antagonist and 5-HT1A receptor agonist.
  31. B2264 Dapoxetine HCl Selective serotonin reuptake inhibitor
  32. B2248 Ketanserin Selective 5-HT2A serotonin receptor antagonist; can also be used to discriminate between 5-HT1D and 5-HT1B receptor subtypes.
  33. B6736 Citalopram hydrobromide New Product
  34. B6799 Indatraline hydrochloride New Product
  35. B6851 Zimelidine dihydrochloride New Product
  36. B6852 S 14506 hydrochloride New Product
  37. B6883 Ipsapirone New Product
  38. B6952 Paroxetine maleate New Product
  39. B6954 (±)-McN 5652 5-HT uptake inhibitor
  40. B7097 Lofepramine New Product
  41. B5292 BTS 54-505 hydrochloride Potent SNRI,sibutramine metabolite
  42. B5406 NAD 299 hydrochloride New Product
  43. B5538 WY 45233 succinate New Product
  44. B5324 Dexfenfluramine hydrochloride New Product
  45. B6659 (S)-WAY 100135 dihydrochloride 5-HT1A receptor antagonist,potent and selective
  46. B6588 (R)-(+)-8-Hydroxy-DPAT hydrobromide New Product
  47. B6292 MDL 73005EF hydrochloride New Product
  48. B6293 MDL 72832 hydrochloride ligand for 5-HT1A receptor, potent and selective
  49. B6337 8-Hydroxy-DPAT hydrobromide New Product
  50. B6349 NAN-190 hydrobromide New Product
  51. B6351 BP 554 maleate Selective 5-HT1A agonist
  52. B6388 CGS 12066B dimaleate New Product
  53. B6410 Anpirtoline hydrochloride New Product
  54. B6457 8-Hydroxy-PIPAT oxalate New Product
  55. B6496 5-Nonyloxytryptamine oxalate New Product
  56. B6511 MM 77 dihydrochloride New Product
  57. B6537 Isamoltane hemifumarate New Product
  58. B6538 Cyanopindolol hemifumarate New Product
  59. B5366 (±)-MDMA hydrochloride New Product
  60. A3144 Adoprazine 5-HT1A receptor agonist and full D2/3 receptor antagonist
  61. A3811 SEA0400 Specific inhibitor of Na+/Ca2+ exchange
  62. A3873 Tianeptine 5-HT facilitator
  63. A3918 Vilazodone Combined SSRI and 5-HT1A receptor partial agonist
  64. A3919 Vilazodone Hydrochloride Combined SSRI and 5-HT1A receptor partial agonist
  65. A3926 Vortioxetine 5-HT receptors antagonist
  66. A3933 WAY-100635 5-HT1A receptor antagonist,potent and selective
  67. A3934 WAY-100635 maleate salt 5-hydroxytryptamine1A antagonist
  68. A3952 Ziprasidone 5-HT (serotonin)/dopamine receptor antagonist
  69. A3953 Ziprasidone hydrochloride monohydrate 5-HT (serotonin)/dopamine receptor antagonist
  70. A1295 Granisetron HCl 5-HT3 receptor antagonist
  71. A1334 Mosapride Citrate 5-HT receptor agonist
  72. A5010 Asenapine Inhibits adrenergic receptor/5-HT receptor
  73. A3796 SB-269970 5-HT7 receptor antagonist
  74. A3778 RS 127445 5-HT2B receptor antagonist,high affinity
  75. A3697 Palonosetron 5-HT3 antagonist
  76. A3157 Alosetron 5-HT3 receptor antagonist
  77. A3158 Alosetron (Z)-2-butenedioate 5-HT3 receptor antagonist
  78. A3159 Alosetron Hydrochloride 5-HT3 receptor antagonist,potent and highly selective
  79. A3160 Alosetron Hydrochloride(1:X) 5-HT3 receptor antagonist
  80. A3192 Asenapine hydrochloride Atypical antipsychotic
  81. A3239 B-HT 920 D2 receptor agonist
  82. A3241 Bilobalide Neuroprotective agent
  83. A3317 Clozapine N-oxide (CNO) Metabolite of clozapine, used in chemogenetics.
  84. A3330 CP-809101 5-HT2C receptor agonist
  85. A3331 CP-809101 hydrochloride 5-HT2C receptor agonist, potent and selective
  86. A3443 Granisetron Serotonin 5-HT3 receptor antagonist
  87. A3569 LY 344864 5-HT1F receptor agonist,potent and selective
  88. A2436 Fluoxetine HCl Serotonin reuptake inhibitor,selective
  89. B1203 Iloperidone hydrochloride Iloperidone (hydrochloride) is a D(2)/5-HT(2) receptor antagonistis, which is an atypical antipsychotic for the treatment of schizophrenia symptoms.
  90. B1198 Cisapride Cisapride(R 51619) is a nonselective 5-HT4 receptor agonist, it is also a potent human ether-à-go-go-related gene (hERG) potassium channel inhibitor.
  91. B2256 SB742457 5-HT6 receptor antagonist,highly selective and high affinity
  92. B2240 Olanzapine 5-HT2A/D2 antagonist
  93. B1199 Tandospirone Anxiolytic and antidepressant reagent
  94. B1058 Lasmiditan 5-HT1F receptor agonist
  95. B2239 Lorcaserin HCl selective full agonist of human 5-HT2C receptor with Ki of 15 nM.
  96. B2254 SB269970 HCl 5-HT7 receptor antagonist,potent and selective
  97. B1200 PRX-08066 5-HT2BR antagonist
  98. B2262 Agomelatine MT1/MT2 / 5-HT2C agonist
  99. B1201 Agomelatine hydrochloride Agomelatine is a competitive antagonist of human and porcine serotonin (5-HT2C) receptors (pKi = 6.2 and 6.4, respectively) as well as human 5-HT2B receptors (pKi = 6.6).
  100. B1202 Agomelatine L(+)-Tartaric acid Agomelatine (L(+)-Tartaric acid) is a antidepressant, which is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.
  101. B1001 Loxapine 5-HT Receptor antagonist
  102. B2245 BRL-54443 5-HT1E/1F receptor agonist,potent and selective
  103. B2265 BRL-15572 5-HT1D receptor antagonist
  104. B1197 Risperidone mesylate Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM).
  105. A2553 Fluvoxamine maleate Serotonin reuptake inhibitor,selective,antidepressant
  106. A5355 Venlafaxine Dual serotonin/noradrenalin re-uptake inhibitor
  107. A5322 Tianeptine sodium 5-HT uptake facilitator,selective,antidepressant
  108. A5294 Sumatriptan Succinate 5-HT1 receptor agonist
  109. A5350 Ziprasidone HCl Serotonin and dopamine receptor antagonist
  110. A5399 Iloperidone Dopamine (D2) and serotonin (5HT2) receptor antagonist
  111. A2547 Vortioxetine (Lu AA21004) HBr 5-HT receptor modulator, antidepressant and anxiolytic
  112. A2098 PRX-08066 Maleic acid 5-HT2B receptor antagonist,potent and selective
  113. A8514 Risperidone SR-2A inhibitor
  114. A8516 Rizatriptan Benzoate Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine.
  115. A8384 Blonanserin Atypical antipsychotic
  116. A8421 Duloxetine HCl Duloxetine HCl is a selective serotonin and norepinephrine reuptake inhibitor .
  117. B1196 Risperidone hydrochloride Risperidone Hcl(R 64 766 Hcl) is a serotonin 5-HT2 receptor blocker(Ki= 0.16 nM) and a potent dopamine D2 receptor antagonist(Ki= 1.4 nM).
  118. A5166 Ondansetron HCl 5-HT3 receptor antagonist
  119. B4981 Sumatriptan 5-HT1 receptor agonist
  120. A3561 Lu AE58054 Hydrochloride 5-HT(6)R antagonist
  121. A3793 SB 271046 hydrochloride Selective 5-HT6 antagonist
  122. A3777 Rotigotine hydrochloride Agonist of dopamine D2/D3 receptor
  123. A3776 Rotigotine Agonist of dopamine D2/D3 receptor
  124. A3748 rac-Rotigotine Hydrochloride Agonist of dopamine D2/D3 receptor
  125. A3560 Lu AE58054 5-HT(6)R antagonist
  126. B1606 Orphenadrine Citrate Antiparkinsonian and analgesic drug
  127. B1608 Tropicamide Antimuscarinic drug
  128. B1595 Succinylcholine Chloride Dihydrate Succinylcholine Chloride Dihydrate is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.
  129. B1594 Neostigmine Bromide Cholinesterase inhibitor
  130. B1607 Otilonium Bromide Otilonium bromide is an antimuscarinic.
  131. B1605 Hyoscyamine Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.
  132. B1604 Homatropine Methylbromide Muscarinic AChR antagonist
  133. B1603 Homatropine Bromide Muscarinic AChR antagonist
  134. B1592 Hexamethonium Bromide Hexamethonium Bromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.
  135. B1611 Methscopolamine Muscarinic acetylcholine receptor blocker
  136. B2252 Paroxetine HCl Antidepressant agents
  137. B3433 Flavoxate hydrochloride Flavoxate Hydrochloride(DW-61 Hydrochloride) is a muscarinic AChR antagonist used in various urinary syndromes and as an antispasmodic.
  138. B3415 Solifenacin hydrochloride Solifenacin Hcl(YM905 Hcl; Vesicare Hcl) is a muscarinic receptor antagonist.
  139. B1597 Arecoline Muscarinic acetylcholine receptors agonist
  140. B1599 Bethanechol chloride Muscarinic receptor agonist
  141. B1596 Acetylcholine Chloride Major transmitter at many nervous sites
  142. B1612 Pancuronium dibromide AChR antagonist
  143. B1610 Gallamine Triethiodide Gallamine Triethiodide is a synthetic nondepolarizing blocking drug.
  144. B1616 Trospium chloride Antimuscarinic agent
  145. B1619 Tiotropium Bromide hydrate Muscarinic antagonist
  146. B1601 Decamethonium Bromide Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent.
  147. B1134 Oxybutynin chloride Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
  148. B1512 Pregnenolone steroid hormone
  149. A8369 Atropine MAChRs antagonist
  150. A8356 Acetylcysteine Antioxidant;mucolytic agent
  151. A5391 Varenicline Tartrate Subtype-selective agonist of α4β2 nicotinic receptors,orally active
  152. A5220 Vecuronium Bromide Nonpolarizing neuromuscular relaxant
  153. A1745 Galanthamine HBr Acetylcholinesterase inhibitor
  154. A1366 Rocuronium Bromide TGF-βR I kinase inhibitor
  155. A3874 Tiotropium Bromide MAChR M antagonist
  156. A3775 Rocuronium Neuromuscular blocker for anaesthesia;aminosteroid
  157. A3138 A-867744 Allosteric Modulator
  158. A8495 Oxybutynin Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
  159. A8515 Rivastigmine Tartrate Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.
  160. A8414 Diphemanil Methylsulfate Diphemanil Methylsulfate is a quaternary ammonium anticholinergic.
  161. B1033 (R)-(+)-Tolterodine Tolterodine is a potent muscarinic receptor antagonists that show selectivity for the urinary bladder over salivary glands in vivo.
  162. B1266 Glycopyrrolate Glycopyrrolate is a muscarinic competitive antagonist used as an antispasmodic.
  163. B1133 Tarafenacin D-tartrate Tarafenacin(SVT-40776) is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over M2 receptor.
  164. B1132 Tarafenacin M3 muscarinic receptor antagonist
  165. B1131 Xanomeline oxalate Muscarinic receptor agonist
  166. B1032 VU0152100 M4 receptor allosteric modulators
  167. B1265 Biperiden Anticholinergic drug
  168. B1615 PNU-120596 α7 nAChR modulator,positive allosteric
  169. A8451 Ipratropium Bromide Ipratropium bromide is a mAChR M (muscarinic) antagonist, bronchodilator. N-Isopropyl salt of atropine.
  170. B5897 ML352 Non-competitive inhibitor of the presynaptic choline transporter
  171. B4828 TBPB
  172. B4823 mAChR-IN-1
  173. B4878 LY2119620 positive allosteric modulator of M2/M4 receptor
  174. B4873 Nitenpyram
  175. B6393 (±)-Vesamicol hydrochloride New Product
  176. A3768 Rivastigmine Cholinesterase inhibitor
  177. A3423 Galanthamine Acetylcholinesterase inhibitor
  178. B1613 Pyridostigmine Bromide Pyridostigmine is a parasympathomimetic and a reversible cholinesterase inhibitor.
  179. B3414 Galanthaminone Cholinesterase(AChE) inhibitor
  180. B4718 (±)-Huperzine A
  181. A8200 DAPT (GSI-IX) Top Seller γ-secretase inhibitor,potent and specific
  182. A8190 Semagacestat (LY450139) Top Seller γ-secretase inhibitor
  183. A1932 (-)-Huperzine A Top Seller NMDA receptor antagonist/AChE inhibitor
  184. A1102 Amyloid β-peptide (10-35), amide Truncated peptide model
  185. A1053 amyloid A protein fragment [Homo sapiens] Apolipoproteins related to HDL in plasma
  186. A1031 Myelin Basic Protein (68-82), guinea pig Myelin Basic Protein
  187. A1005 Beta-Sheet Breaker Peptide iAβ5 Peptide which can inhibit amyloidogenesis
  188. A1004 Amyloid Precursor C-Terminal Peptide For beta amyloid generation
  189. A1003 Amyloid β-Protein (1-15) Principal component of amyloid
  190. A1002 Beta-Amyloid (1-11) Amyloidogenic peptide
  191. A1131 COG 133 ApoE mimetic peptide
  192. A1124 Amyloid Beta-Peptide (1-40) (human) Amyloid precursor protein
  193. A1123 Amyloid Beta-Peptide (12-28) (human) sequence H2N-VHHQKLVFFAEDVGSNK-OH
  194. A1040 Myelin Basic Protein (87-99) Encephalitogenic peptide
  195. A1039 Amyloid Beta-peptide (25-35) (human) Functional domain of Aβ
  196. A1038 Amyloid β-Peptide (10-20) (human) Initiates neurodegeneration in Alzheimer disease
  197. B1325 EUK 134 Salen-manganese complexes;SOD mimetic
  198. B8029 ARN2966 APP expression modulator
  199. B5804 J 147 New Product
  200. B5769 Methoxy-X04 New Product
  201. B7043 Ro 90-7501 New Product

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