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Angiogenesis

  1. Cat.No. Product Name Information
  2. A8668 Thrombin Receptor Agonist Peptide Agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 μM) and secretion.
  3. A8667 AY-NH2 Selective PAR4 receptor agonist peptide. Stimulates platelet aggregation in vitro (EC50 = 15 μM).
  4. A8666 TFLLR-NH2 Peptide derived from the protease-activated receptor-1 (PAR1) that acts as a PAR1 selective agonist (EC50 = 1.9 μM).
  5. A8665 SLIGRL-NH2 Agonist peptide derived from the N-terminus of protease-activated receptor-2 (PAR2).
  6. A8664 A 286982 A 286982 is a selective inhibitor of LFA-1/ICAM-1 binding and LFA-1 with IC50 value of 44 nM and 35 nM, respectively [1].
  7. A8663 BIO 1211 BIO 1211 is a selective and high affinity inhibitor of α4β1 with IC50 value of 0.004uM [1].
  8. A8662 A 205804 Selective inhibitor of E-selectin and ICAM-1 expression (IC50 values are 20, 25 and > 1000 nM for TNF-α-induced E-selectin, ICAM-1 and VCAM-1 expression respectively).
  9. A8661 MNS Selective inhibitor of Src and Syk tyrosine kinases. Displays antiaggregative activity via inhibition of GPIIb/IIIa activation (IC50 = 12.7 μM for thrombin-induced platelet aggregation).
  10. A8660 Cilengitide Cilengitide is a cyclic RGD pentapeptide [Arg-Gly-Asp-DPhe-(NMeVal)], and a potent αvβ3 and αvβ5 integrin inhibitor to block integrin-mediated adhesion and migration.
  11. A8636 RN486 RN486 is a reversible inhibitor of Btk with IC50 value of 4.0 nM [1].

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