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FGF-21, murine recombinant

In stock
Catalog No.
P1009
FGF-21, expressed in E.Coli, suitable for cell culture.
Grouped product items
SizePriceStock Qty
10ug
$275.00
In stock
50ug
$834.00
In stock
1 mg
$7,140.00
In stock

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Background

Fibroblast growth factor 21 (FGF-21) is a member of the FGF family that contains more than 20 small (~17–26 kDa) secreted peptides. FGF-21 is mainly secreted by the liver and can travel through the circulatory system and function as an endocrine hormone. FGFs modulate cellular activity via 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, -4 and -5. FGFRs play an important role in the regulation of glucose and lipid homeostasis. FGF-21 is a potent activator of glucose uptake on adipocytes, protects animals from diet-induced obesity, and lowers blood glucose and triglyceride levels in diabetic rodents.

 Mouse FGF-21 is a 210 amino acid (aa) polypeptide that contains a 120 aa core FGF domain and a hydrophobic N-terminus signal sequence that is cleaved to release the soluble 180 aa mature FGF-21 protein. Recombinant mouse FGF-21 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 183 amino acids including N-terminal Methionine. The amino acid sequence of the recombinant mouse FGF-21 is 100% homologous to the amino acid sequence of the mouse FGF-21 without signal sequence. The FGF-21 is purified by proprietary chromatographic techniques.

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥95%, by SDS-PAGE and HPLC.
    Endotoxin Level:N/A

Related Biological Data

FGF-21

Related Biological Data

FGF-21
 

Description

Gene ID: 56636 Accession #: Q9JJN1
Alternate Names:mouse FGF-21, FGF-21, FGF21, FGF 21, m-FGF-21, rm-FGF-21, recombinant mouse FGF-21, recombinant FGF-21, FGF.
Source: Escherichia Coli. M.Wt: 20.1 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized from filtered (0.4 mm) solution containing 20 mM Tris, pH 7.4 and 20 mM NaCl.
Solubility:Reconstitute in sterile H2O to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition: gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.