Home >> Phosphatase Inhibitor Cocktail (2 Tubes, 100X)
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Phosphatase Inhibitor Cocktail (2 Tubes, 100X) K1012+K1013

Catalog No.K1015
Size Price Stock Qty
1ml A + 1ml B
$37.00
In stock
(1ml A + 1ml B)×10
$270.00
In stock
(1ml A + 1ml B)×50
$1,080.00
In stock
(1ml A + 1ml B)×100
$1,620.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

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Sample solution is provided at 25 µL, 10mM.

Components and storage

Tube # Catalog No. Product Name Summary Targets CAS Number Smiles
A (100X in DMSO)
N1686 Cantharidin Inhibitor of protein phosphatases 1/2A Nature Products 56-25-7 O=C([[email protected]@]1(C([H])([H])[H])[[email protected]]2(C([H])([H])[H])[[email protected]@]3([H])O[[email protected]]1([H])C([H])([H])C3([H])[H])OC2=O
B4750 (-)-p-Bromotetramisole Oxalate ALP inhibitor, potent and non-specific Others|Others 62284-79-1 BrC(C=C1)=CC=C1[[email protected]]2N=C3SCCN3C2.OC(C(O)=O)=O
B3698 Microcystin-LR Inhibitor of protein phosphatase PP1/PP2A,potent and selective Chromatin/Epigenetics|Protein Ser/Thr Phosphatases 101043-37-2 CC1C(NC(=O)C(NC(=O)C(C(NC(=O)C(NC(=O)C(NC(=O)C(=C)N(C(=O)CCC(NC1=O)C(=O)O)C)C)CC(C)C)C(=O)O)C)CCCN=C(N)N)C=CC(=CC(C)C(CC2=CC=CC=C2)OC)C
B (100X in ddH2O)
A8524 Sodium Orthovanadate PTP inhibitor Membrane Transporter/Ion Channel|ATPase 13721-39-6 [O-][V](=O)([O-])[O-].[Na+].[Na+].[Na+]
B7843 Sodium molybdate Acid and phosphoprotein phosphatases inhibitor 7631-95-0 [O-][Mo](=O)([O-])=O.[Na+].[Na+]
B7844 Sodium tartrate Acid phosphatases inhibitor 868-18-8 C(C(C(=O)[O-])O)(C(=O)[O-])O.[Na+].[Na+]
B7845 Imidazole Alkaline phosphatases inhibitor 288-32-4 C1=CN=CN1
B7846 sodium fluoride Acid phosphatases inhibitor 7681-49-4 [F-].[Na+]
Stored at -20°C, and stable for at least 12 months. When kept at 2-8°C, the product remains stable for 2 months.

Description

Protein phosphorylation is an important covalent post-translational modification that can alter the structural conformation of a protein, which then regulates the function, location and specific binding of the target protein. Many cellular processes are regulated by the reversible phosphorylation of proteins and 30% of the proteins are likely to be phosphorylated at some point during their existence.

Endogenous proteins are produced and degraded in a balanced state, so their cellular levels are stable under stable environmental conditions. Crude cell extracts contain a number of endogenous enzymes, such as phosphatases and proteases, which are capable of degrading and modifying proteins in the extracts. The best way to increase the yield of intact proteins is to add inhibitors of those enzymes known to be present.

For Phosphorylation Protection, more inhibitors mean better results. We provide two tubes with 8 inhibitors.

Tube A (Phosphatase Inhibitor Cocktail 1, Catalog No. K1012) inhibits L-isozymes of alkaline phosphatases and serine/threonine protein phosphatases such as protein phosphatases 1 and 2A (PP1 and PP2A). Tube A contains individual components, including Cantharidin, Bromotetramisole and Microcystin LR. Tube A is supplied as a ready-to-use solution in DMSO.

Tube B (Phosphatase Inhibitor Cocktail 2, Catalog No. K1013) inhibits tyrosine protein phosphatases, acid and alkaline phosphatases. Tube B contains individual components, including Sodium orthovanadate, Sodium molybdate, Sodium tartrate, Imidazole and Sodium Fluoride. Tube B is supplied as a ready-to-use solution in ddH2O.

Advantage

Accurate Ingredients:

Clearance of components and concentrations.


Higher efficiency:

Quick achievement, quality assurance.


Lower price:

Our price is less than any of competitor.