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PDGF-BB, human recombinant protein

Catalog No.
P1047
PDGF-BB, platelet-derived growth factor, expressed in E.Coli.
Grouped product items
SizePriceStock Qty
10ug
$251.00
Ship with 5-10 days
50ug
$785.00
Ship with 5-10 days
1mg
$6,138.00
Ship with 5-10 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

The platelet-derived growth factor BB (PDGF-BB) is a member of the PDGF family and is a disulfide-linked homodimer. PDGF family consists of proteins PDGF-A, -B that form three disulfide-linked homodimers (PDGF-AA, -BB and -AB). The PDGFs are stored in platelet α-granules, and are released upon platelet activation. PDGFs signals transfer through receptors PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. However, PDGFR-β interacts with only PDGF-BB and PDGF-AB. PDGF-BB is a potent mitogen for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells and some blood cells.

Recombinant human PDGF-BB is a 24.3 kDa B chain homodimer protein formed by subunits of 109 amino acid residues.

Biological Activity

Determined by the dose-dependent stimulation of thimidine uptake by BALB/c 3T3 cells.
ED50 < 1 ng/ml.          
Specific activity > 1*106 units/mg.          

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥98%, by SDS-PAGE and HPLC.
    Endotoxin Level:< 0.1 ng/μg/span>

Related Biological Data

FGF-21

Related Biological Data

FGF-21
 

Description

Gene ID: 5155 Accession #: P01127
Alternate Names:PDGFB, Human PDGF-BB, h-PDGF-BB, PDGFBB, PDGF BB, PDGF-BB, rh-PDGF-BB, recombinant human PDGF-BB, recombinant PDGF-BB, PDGF.
Source: Escherichia Coli. M.Wt: 24.3 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized with no additives.
Solubility:Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at +4°C for 1 week and -20°C for future use.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.