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PAR 4 (1-6) PAR4 agonist

Catalog No.A8674
Size Price Stock Qty
5mg
$142.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

PAR 4 (1-6)

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Chemical Properties

Cas No. 225779-44-2 SDF Download SDF
Chemical Name (S)-2-((Z)-((S)-2-((Z)-(2-((Z)-(((S)-1-((S)-2-((Z)-(2-amino-1-hydroxyethylidene)amino)-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)(hydroxy)methylene)amino)-1-hydroxyethylidene)amino)-1,5-dihydroxy-5-iminopentylidene)amino)-3-methylbutanoic acid
Canonical SMILES CC([[email protected]@](/N=C(O)/[[email protected]](/N=C(O)/C/N=C(O)/[[email protected]]1([H])CCCN1C([[email protected]](/N=C(O)/CN)([H])CC2=CC=C(O)C=C2)=O)([H])CCC(O)=N)([H])C(O)=O)C
Formula C28H41N7O9 M.Wt 619.68
Solubility Soluble to 1 mg/ml in sterile water Storage Store at -20°C
Physical Appearance White lyophilised solid Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

N-terminal fragment of protease-activated receptor 4 (PAR4) that acts as a PAR4 agonist (EC50 ~ 100 μM). Induces platelet aggregation and annexin V activation with no effect on clotting time. Mimics thrombin-induced increases in IL-8/CXCL8-Luc activity an