Palonosetron HCl

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Palonosetron HCl 5-HT receptor antagonist

Catalog No.B2229

Size	Price	Stock	Qty
10mM (in 1mL DMSO)	$50.00	In stock
25mg	$125.00	In stock
200mg	$732.00	In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Publications citing ApexBio Products

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2017 Jan 19;541(7637):417-420.

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2016 Apr 21;532(7599):398-401.

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Nature Biotechnology.
2017 Jun;35(6):569-576

Cell.
2018 Feb 22;172(5):1007-1021.e17.

Cell.
2017 Nov 30;171(6):1284-1300.e21.

Cell.
2017 Aug 17. pii: S0092-8674(17)30869-3.

Cell.
2017 Jul 13;170(2):312-323

Nat Med.
2018 Jan 29.

Cell.
2017 Apr 6;169(2):286-300.

Cell.
2015 Aug 27;162(5):987-1002.

Cell.
2015 Feb 12;160(4):729-44.

Nature Medicine.
2017 Apr;23(4):493-500.

Cancer Cell.
2018 Mar 12;33(3):401-416.e8.

Cancer Cell.
2017 Aug 14;32(2):253-267.e5.

Cell Stem Cell.
2017 Nov 20. pii: S1934-5909(17)30375-2.

Cancer Cell.
2017 May 8;31(5):635-652.e6.

Immunity.
2018 Jan 16;48(1):59-74.e5.

Immunity.
2017 Oct 17;47(4):635-647.e6.

Immunity.
2016 Jan 19;44(1):88-102

Nat Cell Biol.
2018 Feb;20(2):186-197.

Nat Cell Biol.
2017 Dec 11.

Nat Cell Biol.
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Nat Immunol.
2017 Jun;18(6):654-664.

Sci Transl Med.
2017 Dec 13;9(420). pii: eaal3765.

Sci Transl Med.
2017 Nov 22;9(417). pii: eaan8462.

Nat Neurosci.
2015 Oct;18(10):1464-73.

Cell Host Microbe.
2017 Oct 11;22(4):561-573.e4.

Cell Res.
2016 Sep;26(9):1007-20.

Mol Cell.
2017 Nov 16;68(4):731-744.e9.

Mol Cell.
2017 Oct 5;68(1):210-223.e6.

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Quality Control

Quality Control & MSDS

View current batch:

Purity = 98.00%

Chemical structure

Palonosetron HCl

Palonosetron HCl Dilution Calculator

Palonosetron HCl Molarity Calculator

Chemical Properties

Cas No.	135729-62-3	SDF	Download SDF
Chemical Name	(3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3a,4,5,6-tetrahydro-3H-benzo[de]isoquinolin-1-one;hydrochloride
Canonical SMILES	C1CC2CN(C(=O)C3=C2C(=CC=C3)C1)C4CN5CCC4CC5.Cl
Formula	C19H25ClN2O	M.Wt	332.87
Solubility	Limited solubility	Storage	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request

Background

Palonosetron Hcl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).