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NVP-BAG956 PI3K and PDK1 inhibitor

Catalog No.A3672
Size Price Stock Qty
10mg
$252.00
In stock
50mg
$1,062.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

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Chemical structure

NVP-BAG956

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Chemical Properties

Cas No. 853910-02-8 SDF Download SDF
Synonyms BAG 956
Chemical Name 2-methyl-2-(4-(2-methyl-8-(pyridin-3-ylethynyl)-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)propanenitrile
Canonical SMILES CC1=NC2=CN=C3C=CC(C#CC4=CN=CC=C4)=CC3=C2N1C5=CC=C(C(C)(C#N)C)C=C5
Formula C28H21N5 M.Wt 427.5
Solubility Soluble in DMSO > 10 mM Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

NVP-BAG956(BAG 956) is a potent, ATP-competitive and selective dual PI3K and PDK1 inhibitor in vitro and in vivo,with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 alpha, beta, delta and gamma and PDK1 kinases, respectively.