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NVP-BAG956 |
Sample solution is provided at 25 µL, 10mM.
NVP-BAG956 Dilution Calculator
NVP-BAG956 Molarity Calculator
| Cas No. | 853910-02-8 | SDF | |
| Synonyms | BAG 956 | ||
| Chemical Name | 2-methyl-2-[4-[2-methyl-8-(2-pyridin-3-ylethynyl)imidazo[4,5-c]quinolin-1-yl]phenyl]propanenitrile | ||
| Canonical SMILES | CC1=NC2=CN=C3C=CC(=CC3=C2N1C4=CC=C(C=C4)C(C)(C)C#N)C#CC5=CN=CC=C5 | ||
| Formula | C28H21N5 | M.Wt | 427.51 |
| Solubility | Soluble in DMSO > 10 mM | Storage | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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NVP-BAG956(BAG 956) is a potent, ATP-competitive and selective dual PI3K and PDK1 inhibitor in vitro and in vivo,with IC50 values to be 56, 444, 34, 117 and 240 nM for PI3K p110 alpha, beta, delta and gamma and PDK1 kinases, respectively.
