Search Site
Related Products

Nu 6027

selective CDK1/2 inhibitor

Nu 6027

Catalog No. A1986
Size Price Stock Qty
5mg $50.00 In stock
25mg $200.00 In stock
100mg $680.00 In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

Nu 6027

Biological Activity

Description Nu 6027 is a selective inhibitor of CDK1 and CDK2 with IC50 value of 2.9 and 2.2 µM, respectively.
Targets CDK1 CDK2        
IC50 2.9 µM 2.2 µM        

Nu 6027 Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Nu 6027 Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Chemical Properties

Cas No. 220036-08-8 SDF Download SDF
Chemical Name 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine
Canonical SMILES C1CCC(CC1)COC2=NC(=NC(=C2N=O)N)N
Formula C11H17N5O2 M.Wt 251.28
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition: Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.