|ATR/CDK inhibitor, potent and selective|
Sample solution is provided at 25 µL, 10mM.
|Description||Nu 6027 is a selective inhibitor of CDK1 and CDK2 with IC50 value of 2.9 and 2.2 µM, respectively.|
|IC50||2.9 µM||2.2 µM|
|Cas No.||220036-08-8||SDF||Download SDF|
|Solubility||Soluble in DMSO > 10 mM||Storage||Store at -20°C|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|
|Shipping Condition||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.