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Nu 6027 |
selective CDK1/2 inhibitor |
Sample solution is provided at 25 µL, 10mM.
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
| Description | Nu 6027 is a selective inhibitor of CDK1 and CDK2 with IC50 value of 2.9 and 2.2 µM, respectively. | |||||
| Targets | CDK1 | CDK2 | ||||
| IC50 | 2.9 µM | 2.2 µM | ||||
Nu 6027 Dilution Calculator
Nu 6027 Molarity Calculator
| Cas No. | 220036-08-8 | SDF | Download SDF |
| Chemical Name | 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine | ||
| Canonical SMILES | C1CCC(CC1)COC2=NC(=NC(=C2N=O)N)N | ||
| Formula | C11H17N5O2 | M.Wt | 251.28 |
| Solubility | Soluble in DMSO > 10 mM | Storage | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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NU6027 is a potent inhibitor of cellular ATR activity (IC(50)=6.7 μM) and enhanced hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner.
