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Nilotinib monohydrochloride monohydrate

Catalog No.
A3660
Bcr-Abl inhibitor
Grouped product items
SizePriceStock Qty
100mg
$50.00
In stock
250mg
$70.00
In stock
500mg
$120.00
In stock
1g
$179.00
In stock

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Background

Nilotinib is a inhibitor of BCR-ABL, IC50 < 30nM; for the treatment of chronic myelogenous leukemia.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt583.99
Cas No.923288-90-8
FormulaC28H25ClF3N7O2
SynonymsAMN-107; Tasigna; AMN107
Solubility≥210.8 mg/mL in DMSO, ≥50 mg/mL in EtOH with gentle warming, insoluble in H2O
Chemical Name4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide;hydrate;hydrochloride
SDFDownload SDF
Canonical SMILESCC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5.O.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Chemical structure

Nilotinib monohydrochloride monohydrate

Related Biological Data

Nilotinib monohydrochloride monohydrate

Related Biological Data

Nilotinib monohydrochloride monohydrate