|MK-4827 tosylatePARP1/PARP2 inhibitor|
Sample solution is provided at 25 µL, 10mM.
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|Cas No.||1038915-73-9||SDF||Download SDF|
|Chemical Name||(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carbimidic acid compound with 4-methylbenzenesulfonic acid (1:1)|
|Solubility||Soluble in DMSO||Storage||Store at -20°C|
MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.