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Related Antibodies

Masitinib (AB1010)

tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor

Masitinib (AB1010)

Catalog No. A2942
Size Price Stock Qty
5mg $50.00 In stock
25mg $100.00 In stock
100mg $300.00 In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

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Chemical structure

Masitinib (AB1010)

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Chemical Properties

Cas No. 790299-79-5 SDF Download SDF
Chemical Name 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide
Canonical SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
Formula C28H30N6OS M.Wt 498.64
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition: Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

Masitinib (AB1010) is a tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor with IC50 of 150 ± 80, 200 ± 40 nM for KIT tyrosine phosphorylation and the recombinant wild-type KIT. Masitinib can enhance the antiproliferative effects of gemcitabi