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JAK2 Inhibitor V, Z3

Catalog No.
A3514
Jak2 tyrosine kinase inhibitor
Grouped product items
SizePriceStock Qty
5mg
$460.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Z3 is a novel specific inhibitor of Jak2 tyrosine kinase. Z3 inhibited Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner but was not cytotoxic to cells at concentrations that inhibited kinase activity.

Chemical Properties

Physical AppearanceA solution in ethanol
StorageStore at -20°C
M.Wt344.45
Cas No.195371-52-9
FormulaC23H24N2O
SynonymsZ3; NSC 42834;1-Butanone, 2-methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-
SolubilitySoluble in DMSO or ethanol
Chemical Name2-methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one
SDFDownload SDF
Canonical SMILESCC(CCC1=CC=CC=N1)(C(C2=CC=CC=C2)=O)CCC3=CC=CC=N3
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

JAK2 Inhibitor V, Z3