Search Site
Home >> Signaling Pathways >> Chromatin/Epigenetics >> JAK >> JAK2 Inhibitor V, Z3
Related Products
JAK2 Inhibitor V, Z3Jak2 tyrosine kinase inhibitor

JAK2 Inhibitor V, Z3

Catalog No. A3514
Size Price Stock Qty
5mg $246.00 Ship Within 10-14 Days

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

JAK2 Inhibitor V, Z3 Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

JAK2 Inhibitor V, Z3 Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Chemical Properties

Cas No. 195371-52-9 SDF Download SDF
Synonyms Z3; NSC 42834;1-Butanone, 2-methyl-1-phenyl-4-(2-pyridinyl)-2-[2-(2-pyridinyl)ethyl]-
Chemical Name 2-methyl-1-phenyl-4-(pyridin-2-yl)-2-(2-(pyridin-2-yl)ethyl)butan-1-one
Canonical SMILES CC(CCC1=CC=CC=N1)(C(C2=CC=CC=C2)=O)CCC3=CC=CC=N3
Formula C23H24N2O M.Wt 344.45
Solubility DMSO 10 mg/ml Ethanol 10 mg/ml Storage Store at -20°C
General tips N/A
Shipping Condition N/A

Background

Z3 is a novel specific inhibitor of Jak2 tyrosine kinase. Z3 inhibited Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner but was not cytotoxic to cells at concentrations that inhibited kinase activity.