Toggle Nav


In stock
Catalog No.
coupling activator for racemization-free coupling in peptide synthesis
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
In stock
In stock
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors


A coupling activator for racemization-free coupling in peptide synthesis; An additive for peptide segment coupling in in reducing the extent of configurational loss at the reactive carboxylic acid residue. Carpino L A etc. works demonstrated that the DIC/HOAt system is more effective in preserving configuration for peptide segment coupling than the analogous DIC/HOBt system

in DMF and DCM. [1]

Carpino L A, El-Faham A.  The diisopropylcarbodiimide/1-hydroxy-7-azabenzotriazole system: segment coupling and stepwise peptide assembly[J]. Tetrahedron, 1999, 55(22): 6813-6830.

Chemical Properties

Physical AppearanceA solid
StorageDesiccate at -20°C
Cas No.39968-33-7
Solubility≥6.8mg/mL in DMSO, ≥9.29 mg/mL in EtOH with ultrasonic, ≥3.62 mg/mL in H2O with ultrasonic
Chemical Name3-hydroxytriazolo[4,5-b]pyridine
SDFDownload SDF
Canonical SMILESC1=CC2=C(N=C1)N(N=N2)O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control