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GM-CSF, human recombinant

Catalog No.
P1012
GM-CSF, pleiotropic cytokine, species specific, expressed in E.Coli.
Grouped product items
SizePriceStock Qty
10ug
$366.00
Please inquire
100ug
$1,200.00
Please inquire
1mg
$5,760.00
Please inquire

Tel: +1-832-696-8203

Email: [email protected]

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Background

Granulocyte Macrophage Colony stimulating Factor (GM-CSF) is a cytokine that stimulates the colony formation of granulocyte-macrophage progenitors. GM-CSF is a pleiotropic cytokine and a member of endogenous cytokine family of the hematopoietic system. GM-CSF is mainly produced by activated T cells, B cells, macrophages and mast cells. GM-CSF plays an important role in stimulating the survival, proliferation, differentiation and activation of hematopoietic cells such as granulocytes and monocytes, basophiles and eosonophoiles, neutrophiles, erythroid cells, megakaryocytes and T cells.

 Human GM-CSF is a 144 amino acids, 22kDa glycoprotein. Human and mouse GM-CSF are species specific and exhibit no cross-species reactivity. However, human GM-CSF is active on canine and feline cells. Recombinant human GM-CSF is a 14.6 kDa globular protein containing 128 amino acid residues.

Biological Activity

Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells.
ED50 < 0.1 ng/ml.          
Specific activity > 1*107 units/mg.          

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥98%, by SDS-PAGE and HPLC.
    Endotoxin Level:<0.1 ng/μg

Related Biological Data

GM-CSF

Related Biological Data

GM-CSF
 

Description

Gene ID: 1437 Accession #: P04141
Alternate Names:CSF2, human GM-CSF, GM-CSF,GMCSF, GM CSF, h-GM-CSF, rh-GM-CSF, recombinant human GM-CSF, recombinant GM-CSF.
Source: Escherichia Coli. M.Wt: 14.6 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized from 10 mM Sodium Citrate, pH 3.5.
Solubility:Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.