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EZ Cap™ Human PTEN mRNA (ψUTP)

Catalog No.
R1026
Human PTEN mRNA with Cap 1 structure, modified by ψUTP, providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.
Grouped product items
SizePriceStock Qty
100ug (1mg/mL)
$255.00
In stock
1mg (1mg/mL)
$1,400.00
In stock
5x1mg (1mg/mL)
$5,000.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

PTEN (deletion of phosphatase and tensin homologues on chromosome 10) is a tumor suppressor gene that resists the action of PI3K, which is a key enzyme for anti-apoptotic, pro-tumorigenic Akt activation.

EZ Cap™ Human PTEN mRNA (ψUTP) is provided at a concentration of 1mg/ml. It is co-transcriptional capped which generates a cap 1 structure with high efficiency. Cap 1 structure is more ideal for mammalian systems and possesses higher transcription efficiency than Cap 0 structure (ARCA and mCap). ψUTP and poly (A) tail suppress RNA-mediated innate immune activation and increase the stability and lifetime of the mRNA in vitro and in vivo. Poly (A) tail also plays an important role in enhancing the efficiency of translation initiation.

Description

mRNA Length 1467 nucleotides
Concentration 1 mg/mL
Buffer 1 mM Sodium Citrate, pH 6.4
Storage -40°C or below
General tips Please dissolve it on ice and protect from RNase carefully. Avoid repeated freeze/thaw cycles as possible. Don’t vortex. Upon first use, centrifuge the tube softly and aliquot it into several single use portions. Use RNase-free reagents and materials with appropriate RNase-free technique. Don’t add to the media with serum unless mixing with a transfection reagent.
Shipping Condition ship with dry ice