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Elastase Inhibitor HNE inhibitor

Catalog No.A2579
Size Price Stock Qty
5mg
$100.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

Elastase Inhibitor

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Chemical Properties

Cas No. 111682-13-4 SDF Download SDF
Chemical Name methyl 4-[[(2R)-1-[[(2R)-1-[(2R)-2-[[(2R)-4-chloro-3-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate
Canonical SMILES CC(C(=O)CCl)NC(=O)C1CCCN1C(=O)C(C)NC(=O)C(C)NC(=O)CCC(=O)OC
Formula C20H31ClN4O7 M.Wt 474.94
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

A potent, irreversible inhibitor of human neutrophil elastase (HNE). The structure of the enzyme-inhibitor complex reveals crosslinking of the catalytic residues His-57 and Ser-195 by the peptidyl chloromethylketone.