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EB 47 Potent PARP-1 inhibitor

Catalog No.A4528
Size Price Stock Qty
10mg
$302.00
In stock
50mg
$1,274.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & MSDS

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Chemical structure

EB 47

Biological Activity

EB 47 is a potent inhibitor of PARP1 with IC50 of 45 nM.
Targets PARP1          
IC50 45 nM          

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Chemical Properties

Cas No. 1190332-25-2 SDF Download SDF
Chemical Name 2-(4-((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-carbonyl)piperazin-1-yl)-N-(1-oxoisoindolin-4-yl)acetamide dihydrochloride
Canonical SMILES O[[email protected]]1[[email protected]@H](O)[[email protected]](N(C=N2)C3=C2C(N)=NC=N3)O[[email protected]@H]1C(N4CCN(CC(NC5=CC=CC6=C5CNC6=O)=O)CC4)=O.Cl.Cl
Formula C24H27N9O6.2HCl M.Wt 610.45
Solubility Soluble in DMSO > 10 mM Storage Store at -20°C
Physical Appearance White solid Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

EB 47 is a potent inhibitor of PARP-1 with IC50 of 45 nM.