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EB 47

Catalog No.
Potent PARP-1 inhibitor
Grouped product items
SizePriceStock Qty
Ship with 5-10 days
Ship with 5-10 days

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EB 47 is a potent inhibitor of PARP-1 with IC50 of 45 nM.

Chemical Properties

Physical AppearanceWhite solid
StorageStore at -20°C
Cas No.1190332-25-2
Solubility<30.52mg/ml in DMSO;insoluble in H2O
Chemical Name2-(4-((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-carbonyl)piperazin-1-yl)-N-(1-oxoisoindolin-4-yl)acetamide dihydrochloride
SDFDownload SDF
Canonical SMILESO[[email protected]]1[[email protected]@H](O)[[email protected]](N(C=N2)C3=C2C(N)=NC=N3)O[[email protected]@H]1C(N4CCN(CC(NC5=CC=CC6=C5CNC6=O)=O)CC4)=O.Cl.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Biological Activity

EB 47 is a potent inhibitor of PARP1 with IC50 of 45 nM.
Targets PARP1          
IC50 45 nM          

Quality Control

Quality Control & MSDS

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Chemical structure

EB 47