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DiscoveryProbe™ Cell Cycle/Checkpoint-related Compounds Panel

Catalog No.L1005
Size Price Stock Qty
In stock

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Sample solution is provided at 25 µL, 10mM.

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Featured Products of the Panel

Catalog No. Product Name Summary Targets CAS Number Smiles
A2521 VE-821 ATR kinase inhibitor,potent and selective Cell Cycle/Checkpoint|ATM/ATR 1232410-49-9 CS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C(=O)NC3=CC=CC=C3)N
A8807 MK-8745 Aurora A inhibitor,potent and selective Cell Cycle/Checkpoint|Aurora Kinase 885325-71-3 ClC1=C(F)C(C(N2CCN(CC3=NC(NC4=NC=CS4)=CC=C3)CC2)=O)=CC=C1
A8394 CHIR-124 Chk1 inhibitor,novel and potent Cell Cycle/Checkpoint|Chk 405168-58-3 C1CN2CCC1C(C2)NC3=C4C=C(C=CC4=NC(=O)C3=C5NC6=CC=CC=C6N5)Cl
B1236 BML-277 Chk2 inhibitor,potent and highly selective Cell Cycle/Checkpoint|Chk 516480-79-8 C1=CC(=CC=C1C2=NC3=C(N2)C=C(C=C3)C(=O)N)OC4=CC=C(C=C4)Cl
A1794 LY2835219 CDK4/6 inhibitor,potent and selective Cell Cycle/Checkpoint|Cyclin-Dependent Kinases 1231930-82-7 CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O
A8412 Dinaciclib (SCH727965) Potent CDK inhibitor Cell Cycle/Checkpoint|Cyclin-Dependent Kinases 779353-01-4 CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCCC4CCO
A8882 THZ1 Covalent CDK7 inhibitor,potent and selective Cell Cycle/Checkpoint|Cyclin-Dependent Kinases ClC1=CN=C(N=C1C2=CNC3=CC=CC=C23)NC4=CC=CC(NC(C5=CC=C(NC(/C=C/CN(C)C)=O)C=C5)=O)=C4
A4393 Paclitaxel (Taxol) Antineoplastic agent Cell Cycle/Checkpoint|Cytoskeleton 33069-62-4 O=C(N[[email protected]]([[email protected]](C(O[[email protected]]1C[[email protected]]2(O)C(C)(C)C([[email protected]@H](OC(C)=O)C([[email protected]@]3(C)[[email protected]]([[email protected]@](CO4)(OC(C)=O)[[email protected]]4C[[email protected]@H]3O)([H])[[email protected]@H]2OC(C5=CC=CC=C5)=O)=O)=C1C)=O)O)C6=CC=CC=C6)C7=CC=CC=C7
Download the Cell Cycle/Checkpoint-related Compounds Panel - XLSX       Download the Cell Cycle/Checkpoint-related Compounds Panel - SDF

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Related Biological Data


Related Biological Data

Paclitaxel (Taxol)

Related Biological Data

Paclitaxel (Taxol)

Signaling Pathway

Aurora Kinase Research Area
Aurora Kinase Compare Products
Cyclin-Dependent Kinases Research Area
Cyclin-Dependent Kinases Compare Products


  • Available in stock with overnight delivery and free shipping over $500
  • Cost-effective and competitive price to save your findings
  • Potent, selective and cell-permeable in inhibiting or activating target molecules
  • Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
  • Detailed files describing potency, selectivity and applications etc.
  • Supported by published data from top peer-reviewed journals
  • Guaranteed high quality with NMR and HPLC validation

Storage and Shipping Information

Solubility Soluble in DMSO Storage Desiccate at -20°C
Packaging 96 well plate Form Powder
General tips For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request


A wide range of well-characterized bioactive molecules that covers various targets related to cell cycle/checkpoint, including Chk, CDK and Plk etc. Facilitate your research towards the insights of DNA replication, tumorgenesis and aging etc. Applicable in cellular assays, animal models and drug screenings etc.