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Dexrazoxane HCl (ICRF-187, ADR-529)

Catalog No.
Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
In stock
In stock
In stock
In stock

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Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known. This agent is used to protect the heart against the cardiotoxic side effects

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
Cas No.149003-01-0
Solubility≥15.24mg/mL in DMSO
Chemical Name4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride
SDFDownload SDF
Canonical SMILESCC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Chemical structure

Dexrazoxane HCl (ICRF-187, ADR-529)