Related Products
D-64131 |
Sample solution is provided at 25 µL, 10mM.
D-64131 Dilution Calculator
D-64131 Molarity Calculator
| Cas No. | 74588-78-6 | SDF | |
| Synonyms | D 64131;D64131 | ||
| Chemical Name | (5-methoxy-1H-indol-2-yl)-phenylmethanone | ||
| Canonical SMILES | COC1=CC2=C(C=C1)NC(=C2)C(=O)C3=CC=CC=C3 | ||
| Formula | C16H13NO2 | M.Wt | 251.28 |
| Solubility | DMSO 100 mM Ethanol 20 mM | Storage | Store at -20°C |
| Shipping Condition: | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
||
D-64131 is a novel inhibitor of Tubulin polymerization that competitively binds with [(3)H]colchicine to αβ-Tubulin. D-64131 is cytotoxic and inhibits tumor cell proliferation in vitro (IC50 = 74 nM). D-64131 prevents growth of tumor models in mice following oral administration in vivo. D-64131 has significant potential in cancer treatment.
