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Cyproterone AcetateAndrogen receptor antagonist

Cyproterone Acetate

Catalog No. A8404
Size Price Stock Qty
10mM (in 1mL DMSO) $50.00 In stock
250mg $60.00 In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

Cyproterone Acetate

Cyproterone Acetate Dilution Calculator

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Cyproterone Acetate Molarity Calculator

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Chemical Properties

Cas No. 427-51-0 SDF Download SDF
Chemical Name (1aR,5aR,5bS,8R,8aS,10aS,10bS,10cS)-8-acetyl-4-chloro-8a,10b-dimethyl-2-oxo-1,1a,2,5a,5b,6,7,8,8a,9,10,10a,10b,10c-tetradecahydrocyclopenta[a]cyclopropa[g]phenanthren-8-yl acetate
Canonical SMILES ClC1=C([H])C(C(C([H])([H])C2([H])[H])([H])C(C2(C(C([H])([H])[H])=O)OC(C([H])([H])[H])=O)(C([H])([H])[H])C([H])([H])C3([H])[H])([H])C3([H])C(C1=C([H])C4=O)(C([H])([H])[H])C5([H])C4([H])C5([H])[H]
Formula C24H29ClO4 M.Wt 416.94
Solubility >14.7mg/mL in DMSO Storage Store at -20°C
General tips N/A
Shipping Condition N/A

Background

Cyproterone acetate has antagonistic properties towards the androgen receptor with an IC50 value of 7.1 nM. It can however, also act as a partial agonist of AR at an EC50 of 4.0 μM.