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CC-401 hydrochloride

In stock
Catalog No.
A3287
JNK inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$257.00
In stock
5mg
$234.00
In stock
10mg
$421.00
In stock
50mg
$1,248.00
In stock

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Background

CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. Based on the chemistry of SP600125, another anthrapyrazolone inhibitor of JNK, CC-401 competitively binds the ATP binding site of JNK, resulting in inhibition of the phosphorylation of the N-terminal activation domain of transcription factor c-Jun; decreased transcription activity of c-Jun; and a variety of cellular effects including decreased cellular proliferation.

Chemical Properties

StorageStore at -20°C
M.Wt424.93
Cas No.1438391-30-0
FormulaC22H25ClN6O
SynonymsCC 401;CC401;CC401 HCl
SolubilitySoluble in DMSO
Chemical Name3-[3-(2-piperidin-1-ylethoxy)phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole hydrochloride
SDFDownload SDF
Canonical SMILESC1CCN(CC1)CCOC2=CC=CC(=C2)C3=NNC4=C3C=C(C=C4)C5=NC=NN5.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control

Quality Control & MSDS

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Chemical structure

CC-401 hydrochloride