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CC-401 hydrochloride

Catalog No.
A3287
JNK inhibitor
Grouped product items
SizePriceStock Qty
2mg
$147.00
Ship with 10-15 days
5mg
$219.00
Ship with 10-15 days
10mg
$396.00
Ship with 10-15 days
50mg
$1,172.00
Ship with 10-15 days

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. Based on the chemistry of SP600125, another anthrapyrazolone inhibitor of JNK, CC-401 competitively binds the ATP binding site of JNK, resulting in inhibition of the phosphorylation of the N-terminal activation domain of transcription factor c-Jun; decreased transcription activity of c-Jun; and a variety of cellular effects including decreased cellular proliferation.

Chemical Properties

StorageStore at -20°C
M.Wt424.93
Cas No.1438391-30-0
FormulaC22H25ClN6O
SynonymsCC 401;CC401;CC401 HCl
SolubilitySoluble in DMSO
Chemical Name3-[3-(2-piperidin-1-ylethoxy)phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole hydrochloride
SDFDownload SDF
Canonical SMILESC1CCN(CC1)CCOC2=CC=CC(=C2)C3=NNC4=C3C=C(C=C4)C5=NC=NN5.Cl
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Quality Control & MSDS

View current batch:

Chemical structure

CC-401 hydrochloride