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SCF, human recombinant protein

In stock
Catalog No.
P1036
SCF, hematopoietic growth factor, expressed in E.Coli.
Grouped product items
SizePriceStock Qty
10ug
$228.00
In stock
50ug
$594.00
In stock
1 mg
$4,020.00
In stock

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Background

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor at the early stages of hematopoiesis. SCF promotes the survival, differentiation, and mobilization of myeloid, erythroid, megakaryocytic, lymphoid, germ cell and melanocyte progenitors. SCF exists in two forms: cell surface bound SCF and soluble SCF. Soluble SCF is produced by the cleavage of surface bound SCF by metalloproteases.

 The human SCF cDNA encodes a 273 aa protein contains a 25 aa signal sequence, a 189 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 36 amino acid cytoplasmic domain. Human SCF shows low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant human SCF is a 18.4 kDa protein containing 165 amino acid residues.

Biological Activity

Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells.
ED50 < 2 ng/ml.          
Specific activity > 5*105 units/mg.          

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥98%, by SDS-PAGE and HPLC.
    Endotoxin Level:<0.1 ng/μg

Related Biological Data

SCF
 

Description

Gene ID: 4254 Accession #: P21583
Alternate Names:Human SCF, SCF, h-SCF, rh-SCF, recombinant human SCF, recombinant SCF.
Source: Escherichia Coli. M.Wt: 18.9 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized from 10 mM Acetic Acid.
Solubility:Reconstitute in sterile water to a concentration of 0.1-1 μg/μl. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.