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TGF-beta1, human recombinant protein (CHO cells)

In stock
Catalog No.
P1039
TGF-β1, pleiotropic cytokine, expressed in CHO cells.
Grouped product items
SizePriceStock Qty
5ug
$330.00
In stock
50ug
$1,980.00
In stock
500ug
$9,540.00
In stock

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Background

Transforming Growth Factor-β1 (TGF-β1) is a pleiotropic cytokine mainly produced by platelets and bone, and regulates cell proliferation, growth, differentiation and motility. TGF-β1 is involved in embryogenesis, tissue remodeling, wound healing, hematopoiesis and endothelial differentiation.

The human TGF-β1 cDNA encodes a 390 aa dimeric inactive precursor protein, which is cleaved to an active dimer of 112 residues disulphide-linked peptides. Recombinant human TGF-β1 is a 25.0 kDa protein containing two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Biological Activity

Determined by the ability of TGF-β1 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells.
ED50 < 0.05 ng/ml.          
Specific activity > 2*107 units/mg.          

Quality Control

Quality Control & DataSheet

View current batch:
    Purity: ≥98%, by SDS-PAGE and HPLC.
    Endotoxin Level:< 0.1 ng/μg

Related Biological Data

FGF-21

Related Biological Data

FGF-21
 

Description

Gene ID: 7040 Accession #: P01137
Alternate Names:TGFB1, Human TGF-beta1, TGF-beta1, TGF beta1, TGFbeta1, h-TGF-beta1, rh-TGF-beta1, recombinant human TGF-beta1, recombinant TGF-beta, TGF.
Source: CHO cells. M.Wt: 25.0 kDa
Appearance: Lyophilized protein Storage: Store at -20°C
Formulation:Lyophilized from Sodium Citrate, pH3.5 buffer.
Solubility:Reconstitution in water to a concentration of 50 ug/ml (e.g., 5 ug/100 ul) will yield a solution of 1 mM citrate buffer (pH 3.5). The solution can then be stored at 4°C for 1 month. It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at -20℃.
Shipping Condition: Gel pack. Handling: Centrifuge the vial prior to opening.
Usage:For Research Use Only! Not to be used in humans.