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Bosentan Endothelin receptor antagonist

Catalog No.B1682
Size Price Stock Qty
10mM (in 1mL DMSO)
$50.00
In stock
50mg
$80.00
In stock
100mg
$140.00
In stock
200mg
$220.00
In stock
500mg
$450.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Quality Control

Chemical structure

Bosentan

Bosentan Dilution Calculator

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Bosentan Molarity Calculator

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Chemical Properties

Cas No. 147536-97-8 SDF Download SDF
Synonyms N/A
Chemical Name 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
Canonical SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC
Formula C27H29N5O6S M.Wt 551.63
Solubility ≥26.45mg/mL in DMSO Storage Store at -20°C
Physical Appearance A solid Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Bosentan is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.