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Betulinic acid

In stock
Catalog No.
A3237
Anti-HIV and antitumor compound,pentacyclic triterpenoid
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
100mg
$50.00
In stock
200mg
$85.00
In stock
500mg
$180.00
In stock

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Background

Betulinic acid is a natural pentacyclic triterpenoid that displays anti-HIV and antitumor activity. Betulinic acid selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic acid also displays TGR5 agonist activity (EC50 =1.04 μM).

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt456.7
Cas No.472-15-1
FormulaC30H48O3
SynonymsLupatic acid,Betulic acid,Mairin,NSC113090,NSC-113090
Solubility≥22.85 mg/mL in DMSO, ≥9.62 mg/mL in EtOH with ultrasonic and warming, <2.73 mg/mL in H2O
Chemical Name(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carboxylic acid
SDFDownload SDF
Canonical SMILESCC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C(=O)O
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control