Beclomethasone|Corticosteroid used for asthma and rhinitis|CAS# 5534-09-8

Size	Price	Stock
10mM (in 1mL DMSO)	$80.00	In stock
5mg	$50.00	In stock
10mg	$60.00	In stock
50mg	$70.00	In stock

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Quality Control

Quality Control & MSDS

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Purity = 99.55%

Chemical structure

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Chemical Properties

Cas No.	5534-09-8	SDF	Download SDF
Synonyms	N/A
Chemical Name	[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
Canonical SMILES	CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)Cl)O)C)C)OC(=O)CC
Formula	C28H37ClO7	M.Wt	521.04
Solubility	≥16.95mg/mL in DMSO	Storage	Store at -20°C
Physical Appearance	A solid	Shipping Condition	Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis [1].

Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis. In addition, Beclomethasone dipropionate has been reported to be previously developed as aqueous nasal formulations for the treatment of Allergic rhinitis. Moreover, Beclomethasone dipropionate has shown the availability in dry nasal aerosol formulations as chiorofluoro carbon metered-dose inhaler nasal sprays [1].

References:
[1] Ratner PH1, Melchior A, Dunbar SA, Tantry SK, Dorinsky PM. Pharmacokinetic profile of beclomethasone dipropionate hydrofluoroalkane after intranasal administration versus oral inhalation in healthy subjects: results of a single-dose, randomized, open-label, 3-period crossover study. Clin Ther. 2012 Jun;34(6):1422-31.