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Beclomethasone dipropionate

Catalog No.
B1248
Corticosteroid used for asthma and rhinitis
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$75.00
In stock
5mg
$37.00
In stock
10mg
$41.00
In stock
50mg
$50.00
In stock

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Email: [email protected]

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Background

Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis [1].

Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis. In addition, Beclomethasone dipropionate has been reported to be previously developed as aqueous nasal formulations for the treatment of Allergic rhinitis. Moreover, Beclomethasone dipropionate has shown the availability in dry nasal aerosol formulations as chiorofluoro carbon metered-dose inhaler nasal sprays [1].

References:
[1] Ratner PH1, Melchior A, Dunbar SA, Tantry SK, Dorinsky PM. Pharmacokinetic profile of beclomethasone dipropionate hydrofluoroalkane after intranasal administration versus oral inhalation in healthy subjects: results of a single-dose, randomized, open-label, 3-period crossover study. Clin Ther. 2012 Jun;34(6):1422-31.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt521.04
Cas No.5534-09-8
FormulaC28H37ClO7
Solubilityinsoluble in H2O; ≥12.72 mg/mL in EtOH with ultrasonic; ≥16.95 mg/mL in DMSO
Chemical Name[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
SDFDownload SDF
Canonical SMILESCCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)Cl)O)C)C)OC(=O)CC
Shipping ConditionShip with blue ice, or upon other requests.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.

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