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B-Raf inhibitor 1 Potent and selective B-Raf inhibitor

Catalog No.B1172
Size Price Stock
5mg
$125.00
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10mg
$200.00
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50mg
$873.00
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100mg
$1,570.00
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Sample solution is provided at 25 µL, 10mM.

Quality Control

Chemical structure

B-Raf inhibitor 1

B-Raf inhibitor 1 Dilution Calculator

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Chemical Properties

Cas No. 1093100-40-3 SDF Download SDF
Chemical Name 1-N-(4-chlorophenyl)-6-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine
Canonical SMILES CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6
Formula C26H19ClN8 M.Wt 478.94
Solubility ≥47.9mg/mL in DMSO Storage Store at -20°C
Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively.