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Arecoline Muscarinic acetylcholine receptors agonist

Catalog No.B1597
Size Price Stock Qty
500mg
$76.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & MSDS

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Chemical structure

Arecoline

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Chemical Properties

Cas No. 300-08-3 SDF Download SDF
Chemical Name methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrobromide
Canonical SMILES CN1CCC=C(C1)C(=O)OC.Br
Formula C8H13NO2.HBr M.Wt 236.11
Solubility Soluble in DMSO Storage Store at -20°C
Physical Appearance A crystalline solid Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Arecoline is a natural alkaloid that is found in the betel nut of the Areca palm. It is an agonist of the muscarinic acetylcholine receptors with EC50 values of 7, 95, 11, 410, and 69 nM for M1, M2, M3, M4, and M5, respectively. Generally, arecoline causes smooth muscle contraction. Arecoline and other muscarinic receptor agonists have been shown to improve learning and memory and may prove to be useful in treating dementia