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ANP (1-11), rat

Catalog No. A1009
Size Price Stock Qty
1mg $30.00 In stock
5mg $90.00 In stock
10mg $150.00 In stock
25mg $210.00 In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

ANP (1-11), rat

ANP (1-11), rat Dilution Calculator

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Chemical Properties

Cas No. SDF Download SDF
Synonyms H2N-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH
Canonical SMILES N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CS)C(N[C@@H](CC1=CC=CC=C1)C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Formula C49H84N20O15S M.Wt 1225.38
Solubility Storage Store at -20°C
General tips N/A
Shipping Condition N/A

Background

Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, angiotensin II stimulation, endothelin, and sympathetic stimulation. ANP is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). It is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes), in response to high blood pressure. ANP acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure.

A1009_1

Ref:

1. Widmaier, Eric P.; Hershel Raff, Kevin T. Strang (2008). Vander's Human Physiology, 11th Ed.. McGraw-Hill. pp. 291, 509–10.

2. Marieb Human Anatomy & Physiology 9th edition, chapter:16, page:629, question number:14

3. de Bold A (1985). "Atrial natriuretic factor: a hormone produced by the heart". Science 230 (4727): 767–70.