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Amitriptyline HCl

In stock
Catalog No.
B2231
Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor
Grouped product items
SizePriceStock Qty
10mM (in 1mL DMSO)
$50.00
In stock
Evaluation Sample
$28.00
In stock
50mg
$68.00
In stock

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Background

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.

Chemical Properties

StorageStore at -20°C
M.Wt313.86
Cas No.549-18-8
FormulaC20H23N.HCl
Solubility≥15.693mg/mL in DMSO
Chemical Name3-(5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride
SDFDownload SDF
Canonical SMILESCN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Shipping ConditionEvaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Quality Control