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AMD 3465 hexahydrobromide potent, selective CXCR4 antagonist

Catalog No.B3397
Size Price Stock Qty
5mg
$78.00
In stock
10mg
$148.00
In stock
25mg
$332.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & MSDS

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Chemical structure

AMD 3465 hexahydrobromide

AMD 3465 hexahydrobromide Dilution Calculator

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Chemical Properties

Cas No. 185991-07-5 SDF Download SDF
Chemical Name N-(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1-(pyridin-2-yl)methanamine
Canonical SMILES N1(CC2=CC=C(CNCC3=NC=CC=C3)C=C2)CCNCCCNCCNCCC1
Formula C24H38N6.6HBr M.Wt 896.07
Solubility Soluble in DMSO Storage Store at -20°C
Physical Appearance A crystalline solid Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

AMD 3465 6HBr(GENZ-644494) is a potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100; inhibits SDF-1α-ligand binding (Ki = 41.7 nM).