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AG-490 (Tyrphostin B42)EGFR/JAK2/JAK3 inhibitor

AG-490 (Tyrphostin B42)

Catalog No. B1493
Size Price Stock Qty
Evaluation Sample $28.00 In stock
10mg $40.00 In stock
25mg $70.00 In stock

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & MSDS

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Chemical structure

AG-490 (Tyrphostin B42)

AG-490 (Tyrphostin B42) Dilution Calculator

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Chemical Properties

Cas No. 133550-30-8 SDF Download SDF
Chemical Name (E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
Canonical SMILES C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
Formula C17H14N2O3 M.Wt 294.3
Solubility Soluble in DMSO > 10 mM Storage Store at -20°C
General tips N/A
Shipping Condition N/A

Background

AG-490 (Tyrphostin B42) is an inhibitor of EGFR with IC50 of 0.1 μM, 135-fold more selective for EGFR versus ErbB2, also inhibits JAK2 with no activity to Lck, Lyn, Btk, Syk and Src.