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Adrenomedullin (1-12), human Vasodilator

Catalog No.A1001
Size Price Stock Qty
5mg
$45.00
In stock
10mg
$75.00
In stock
25mg
$105.00
In stock

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

Adrenomedullin (1-12), human

Adrenomedullin (1-12), human Dilution Calculator

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Chemical Properties

Cas No. SDF Download SDF
Synonyms H2N-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-OH
Canonical SMILES N[[email protected]@H](CC1=CC=C(O)C=C1)C(N[[email protected]@H](CCCNC(N)=N)C(N[[email protected]@H](CCC(N)=O)C(N[[email protected]@H](CO)C(N[[email protected]@H](CCSC)C(N[[email protected]@H](CC(N)=O)C(N[[email protected]@H](CC(N)=O)C(N[[email protected]@H](CC2=CC=CC=C2)C(N[[email protected]@H](CCC(N)=O)C(NCC(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Formula C64H100N22O19S M.Wt 1513.68
Solubility >151.3mg/mL in DMSO Storage Store at -20°C
Shipping Condition Evaluation sample solution : ship with blue ice.All other available size: ship with RT , or blue ice upon request
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.

Background

Adrenomedullin (AM) (1-12), human (C64H100N22O19S1), is a peptide with the sequence Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg. It was first discovered to be associated with pheochromocytoma, a tumor arising from adrenal medulla, in 1993. AM was initially identified as a vasodilator, and as such, it has the ability to relax vascular tone. Previous research cited it as the most potent endogenous vasodilatory peptide found in the body. Other effects of AM include the increase of cell tolerance to oxidative stress and hypoxic injury and angiogenesis. AM is seen as a positive influence in diseases such as hypertension, myocardial infarction, chronic obstructive pulmonary disease and other cardiovascular conditions.

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