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AdaphostinP210bcr/abl tyrosine kinase inhibitor

Adaphostin

Catalog No. A8602
Size Price Stock Qty
10mg $153.00 Ship Within 7 Days
50mg $644.00 Ship Within 7 Days

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Sample solution is provided at 25 µL, 10mM.

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Chemical structure

Adaphostin

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Chemical Properties

Cas No. 241127-58-2 SDF Download SDF
Chemical Name 1-adamantyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate
Canonical SMILES C1C2CC3CC1CC(C2)(C3)OC(=O)C4=CC=C(C=C4)NCC5=C(C=CC(=C5)O)O
Formula C24H27NO4 M.Wt 393.48
Solubility Soluble in DMSO > 10 mM Storage Store at +4°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

p210bcr/abl tyrosine kinase inhibitor (IC50 = 14 μM). Induces apoptosis in T-lymphoblastic human leukemia cell lines (IC50 values range from 16.8 to 216.3 nM) in vitro. Displays selectivity for chronic myelogenous leukemia (CML) myeloid progenitors in vit