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7-xylosyltaxol

taxol (Paclitaxel) derivative

7-xylosyltaxol

Catalog No. A3128
Size Price Stock Qty
10mg $359.00 Ship Within 7 Days
25mg $617.00 Ship Within 7 Days

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Sample solution is provided at 25 µL, 10mM.

7-xylosyltaxol Dilution Calculator

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Chemical Properties

Cas No. 90332-66-4 SDF Download SDF
Synonyms 7-Xylosylpaclitaxel; Taxol-7-xyloside
Chemical Name 7-Xylosylpaclitaxel; Taxol-7-xyloside
Canonical SMILES CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)OC8C(C(C(CO8)O)O)O)C)OC(=O)C
Formula C52H59NO18 M.Wt 986.02
Solubility Soluble in DMSO Storage Store at -20°C
Shipping Condition: Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Background

7-xylosyltaxol is a taxol (Paclitaxel) derivative. Paclitaxel is a compound extracted from the Pacific yew tree with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. Paclitaxel also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). Paclitaxel inhibits DNA synthesis and stimulates the release of tumor necrosis factor-α. Paclitaxel induces apoptosis in murine mammary carcinoma MCA-4 and ovarian carcinoma OCA-1 tumors.