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1-Naphthyl PP1Src family kinases inhibitor

1-Naphthyl PP1

Catalog No. A8605
Size Price Stock Qty
10mg $259.00 Ship Within 10-14 Days
50mg $1,088.00 Please Inquire

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Sample solution is provided at 25 µL, 10mM.

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Quality Control & MSDS

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Chemical structure

1-Naphthyl PP1

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Chemical Properties

Cas No. 221243-82-9 SDF Download SDF
Chemical Name 1-tert-butyl-3-naphthalen-1-ylpyrazolo[3,4-d]pyrimidin-4-amine
Canonical SMILES CC(C)(C)N1C2=C(C(=N1)C3=CC=CC4=CC=CC=C43)C(=NC=N2)N
Formula C19H19N5 M.Wt 317.39
Solubility Soluble in DMSO > 10 mM Storage Store at +4°C
General tips N/A
Shipping Condition N/A

Background

Selective inhibitor of src family kinases v-Src and c-Fyn as well as the tyrosine kinase c-Abl. (IC50 values are 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively). Preferentially inhibits mutant over wild-type kinases (IC